Our Team
From L to R: Savarna Goutam, Kate Livingston, Tanner Waldman, Leszek Kotula, Kevin Lin, Anna Seidl, Maria Ortiz
Anna Seidl
Kevin Lin
MD/PhD Student, G2
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Project Summary: Castrate-resistant prostate cancer (CRPC) has a high morbidity rate due to metastasis and treatment inefficacy. Previous work in our lab has identified ABI1 as a key regulator of prostate cancer progression. My research project focuses on how changes in ABI1 may contribute to the mechanisms behind therapy resistance in CRPC through ABI1's roles in androgen receptor activation and transcriptional regulation.
PhD Candidate, 3rd Year
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Project Summary: Anti-androgen therapy during prostate cancer treatment has been shown to cause cognitive deficits, also known as treatment-induced dementia. My research project aims to investigate the hypothesis that ABI1, a well-characterized actin cytoskeleton regulator modulated by androgen receptor activity, plays a role in the regulation of dendritic spine morphology in neurons.
Kate Livingston
PhD Student, 2nd Year​
Project Summary: ABI1 has been shown to undergo alternative splicing during prostate cancer progression to include DNA-binding domains which we hypothesize to regulate transcription. My project will investigate the mechanisms through which ABI1 may regulate transcription.
Tanner Waldman
Senior Research Support Specialist- Bioinformatics
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